Researchers find novel way to target Triple-Negative Breast Cancer
If we think of cancer cells as a house, the receptors are the locks of the house’s front door. Triple-Negative Breast Cancer (TNBC) is more challenging to handle as it does not express commonly found breast cancer receptors, e.g., Estrogen (ER) and Progesterone (PR). This leaves doctors with less options to destroy the cancer cells.
A team of researchers led by Dr Dipak Dutta, Principal Scientist at the Cancer Biology division of CSIR-Central Drug Research Institute (CDRI), Lucknow, has come up with a new and striking mechanism for EZH2-histone trimethylation-mediated gene upregulation instead of its classical suppressive function. Apart from Dr Dutta, the CDRI researchers team comprised Ayushi Verma, Akhilesh Singh, Manish Pratap Singh, Mushtaq Ahmad Nengroo, Krishan Kumar Saini, ...
